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Renal Cell Carcinoma: Molecular Targets and Clinical Applications
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ISBN13: 9781493950638
Publisher: Springer
Published: Aug 23 2016
Pages: 613
Weight: 1.92
Height: 1.27 Width: 6.10 Depth: 9.25
Language: English
Table of Contents
Renal Cell Carcinoma: Molecular Targets & Clinical Applications, 3rd Edition
Editors: Ronald M. Bukowski, M.D., Robert Figlin, M.D., Robert Motzer, M.D.
Ch. 1: Targeted Therapy for Metastatic Renal Cell Carcinoma: the First Ten Years
Ronald M. Bukowski, M.D., Robert Figlin, M.D., Robert Motzer, M.D.
Ch. 2: RCC: Pathologic and Molecular assessment of Targets
Ferran Algaba, M.D.
Ch. 3: Targeted Therapy for Metastatic Renal Cell Carcinoma: the First Ten Years
Stephen M. Keefe, M.D., W. Kimryn Rathmell, M.D., Ph.D., Katherine L. Nathanson, M.D.
Ch. 4: VHL and HIF in clear cell Renal Cell Carcinoma: Molecular Abnormalities and Potential Clinical Applications
Lucy Gossage, M.R.C.P., M.Sc.
Ch. 5: PBRM1: A Critical Subunit of the SWI/SNF Chromatin Remodeling Complex
Chung-Han Lee, M.D., Ph.D., Can G. Pham, Ph.D., James J. Hsieh, M.D., Ph.D.
Ch. 6: Sporadic RCC - Abnormalities in Histone Modifying Genes
Ruhee Dere, Ph.D., Thai H. Ho, M.D., Ph.D.
Ch. 7: Genetic Heterogeneity in Renal Cell Carcinoma: Clinical Implications?
Susan A.J. Vaziri, Ph.D, Mahrukh K. Ganapathi, Ph.D, Ram N. Ganapathi, Ph.D.
Ch. 8: First-Generation Tyrosine Kinase Inhibitors - Clinical Results
Han Hsi Wong, Ph.D. Tim Eisen, Ph.D., F.R.C.P.
Ch. 9: Second Generation Tyrosine Kinase Inhibitors (Pazopanib) in Renal Cell Carcinoma: Current Status
Linda Cerbone, M.D., Cora N. Sternberg, M.D., F.A.C.P.
Ch. 10: Third Generation TKIs (Axitinib, Tivozanib) in RCC: enhanced efficacy and diminished toxicity?
Hui Zhu, M.D., Ph.D., Brian I. Rini, M.D. F.A.C.P.,
Ch. 11: Anti-VEGF and VEGFR monoclonal antibodies in RCC
Bernard Escudier, M.D., Laurence Albiges, M.D.
Ch. 12: PI3-Kinase, Akt, and mTOR Inhibitors in RCC
Daniel C. Cho, M.D., James W. Mier, M.D.
Ch. 13: Carbonic anhydrase IX & Monoclonal Antibody G250: relevance as a clinical and biologic target in Renal Cell Carcinoma
Egbert Oosterwijk, Ph.D., Otto C. Boerman, Ph.D., Jeannette C. Oosterwijk-Wakka, B.Sc. Wim J. Oyen, M.D., Ph.D., Peter F. A. Mulders, M.D., Ph.D.
Ch. 14: EGFR and HER2: Relevance in Renal Cell Carcinoma
Sarathi Kalra, M.D., Eric Jonasch, M.D.
Ch. 15: The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma
Fabiola Cecchi, Ph.D., Young H. Lee, Ph.D., Benedetta Peruzzi, Ph.D., Jean-Baptiste Lattouf, M.D. Donald P. Bottaro, Ph.D.
Ch. 16: Development of Resistance to Targeted Therapy: Preclinical Findings and Clinical Relevance
James W. Mier, M.D., Rupal S. Bhatt, M.D., Ph.D., David J. Panka, Ph.D., Michael B. Atkins, M.D.
Ch. 17: Development of Combination Therapy with Targeted Agents
C. Lance Cowey, M.D., Thomas E. Hutson, D.O., Pharm.D., F.A.C.P.
Ch. 18: Side Effects of Targeted Thearpy
Luis Leon, M.D., Luis Miguel Anton Aparicio, M.D., Emilio Esteban Gonzalez, M.D., Martin Lazaro Quintela, Ph.D., Sergio Vazquez Estevez, M.D.
Ch. 19: The Role of Targeted Therapy in Special Populations
James M.G. Larkin, Ph.D., F.R.C.P., Martin E. Gore, Ph.D., F.R.C.P.
Ch. 20:
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