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Recent Advances in HTLV Research 2015

Recent Advances in HTLV Research 2015

Paperback

Biology

ISBN10: 3038423769
ISBN13: 9783038423768
Publisher: Mdpi Ag
Published: Feb 24 2017
Pages: 308
Weight: 1.46
Height: 0.84 Width: 6.69 Depth: 9.61
Language: English

The human T-cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) were both discovered over three decades ago and infect millions people worldwide. HTLV-1 is associated with the adult T-cell leukemia/lymphoma (ATLL) in about 2% of individuals infected, and another 2 to 3% of individuals develop a neurologic disorder called HTLV-associated myelopathy (HAM). HTLV-2 causes HAM in approximately 1 to 2% of infected individuals, but does not cause ATLL. HTLV-1 and HTLV-2 have served as excellent models for the study of the epidemiology and pathogenesis of virus-associated cancers as well as autoimmune conditions such as multiple sclerosis. Recently, two new members--HTLV-3 and HTLV-4--have been discovered in bushmeat hunters from central Africa, which emphasizes the urgent need for continual surveillance for new human retroviruses and their capacity to cause disease.

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Biology