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Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine

Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine

Hardcover

Medical ReferenceOther Animals

ISBN10: 1493905082
ISBN13: 9781493905089
Publisher: Springer Nature
Published: Mar 29 2014
Pages: 233
Weight: 1.35
Height: 0.90 Width: 6.30 Depth: 9.20
Language: English
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene - KCNJ5 - in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.

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