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NanopartÃculas magnéticas revestidas com pullulan para terapia hipertermica
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ISBN10: 6209047599
ISBN13: 9786209047596
Publisher: Edicoes Nosso Conhecimento
Published: Sep 22 2025
Pages: 80
Weight: 0.26
Height: 0.19 Width: 6.00 Depth: 9.00
Language: Portuguese
ISBN13: 9786209047596
Publisher: Edicoes Nosso Conhecimento
Published: Sep 22 2025
Pages: 80
Weight: 0.26
Height: 0.19 Width: 6.00 Depth: 9.00
Language: Portuguese
As nanopartÃculas magnéticas têm atraÃdo cada vez mais atenção devido à s suas potenciais aplicações em muitos campos industriais, estendendo-se até mesmo ao uso em aplicações biomédicas, como sistemas de administração de medicamentos, implantes, biossensores, laboratórios em chip, aprimoramento de imagens, terapia hipertermica e assim por diante. Para melhores aplicações experimentais, as nanopartÃculas magnéticas são encapsuladas. O material de revestimento utilizado neste estudo é o pullulan. O pullulan é um expansor de plasma não tóxico e não imunogénico que é revestido com nanopartÃculas magnéticas. A acetilação do pullulan é realizada utilizando o método de Motozato e, juntamente com isso, foi preparado um gel magnético. As nanopartÃculas magnéticas revestidas com acetato de pullulan foram o resultado da combinação de acetato de pullulan e nanopartÃculas magnéticas pelo método de difusão de solvente. A amostra foi caracterizada utilizando XRD (difração de raios X), FTIR (espectroscopia de infravermelho por transformada de Fourier), SEM (microscopia eletrónica de varrimento), VSM (magnetometria de amostra vibratória) e DLS (espalhamento dinâmico de luz). Estudos de biocompatibilidade mostram a percentagem de viabilidade celular com diferentes concentrações de amostras. O material foi verificado quanto ao aumento da temperatura, variando o campo magnético e a intensidade do campo.
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