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Phosphoinositide 3-Kinase in Health and Disease: Volume 1

Phosphoinositide 3-Kinase in Health and Disease: Volume 1

Hardcover

Series: Current Topics in Microbiology and Immmunology, Book 346

Medical ReferenceAnatomy & Physiology

ISBN10: 3642136621
ISBN13: 9783642136627
Publisher: Springer
Published: Oct 1 2010
Pages: 310
Weight: 1.70
Height: 1.10 Width: 6.10 Depth: 9.20
Language: English
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here

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