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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
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Pharmacology of Hormonal Polypeptides and Proteins: Proceedings of an International Symposium on the Pharmacology of Hormonal Polypeptides, Held in Mi

Pharmacology of Hormonal Polypeptides and Proteins: Proceedings of an International Symposium on the Pharmacology of Hormonal Polypeptides, Held in Mi

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Paperback

Series: Advances in Experimental Medicine and Biology, Book 2

Medical ReferenceBiologyChemistry

ISBN10: 1489927263
ISBN13: 9781489927262
Publisher: Springer
Published: Dec 7 2013
Pages: 660
Weight: 2.54
Height: 1.36 Width: 7.00 Depth: 10.00
Language: English
It can be concluded (under the specific experimental procedures em- ployed) that: - 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig- nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport- ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: - the first phase, when there is only an inflow from the circulation and stor- age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in- flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y., U. S. A. andbyGrantNo.

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