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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Pharmacokinetic Challenges in Drug Discovery

Pharmacokinetic Challenges in Drug Discovery

Pelkonen, O.
Baumann, A.
Reichel, A.

Paperback

Series: Ernst Schering Foundation Symposium Proceedings, Book 37

Medical ReferenceChemistry

ISBN10: 3662043858
ISBN13: 9783662043851
Publisher: Springer Nature
Published: Dec 16 2012
Pages: 306
Weight: 0.85
Height: 0.68 Width: 5.83 Depth: 8.27
Language: English
Despite increased spending on research and development, the number of new medicines marketed successfully continues to decline. The Pharmaceutical industry is therefore focussing on ways to reduce attrition by addressing frequent reasons for clinical drug failures very early in the drug discovery process. One of the biggest challenges is the pharmacokinetic (PK) optimisation of drug candidates tailored and predicted to have appropriate absorption, distribution, metabolism and excretion (ADME) characteristics in human. This book describes how traditional pbarmacokinetic approaches and methods are being re-invented' to meet specific needs dictated by the dynamics of the drug discovery process. The book gives an overview of state-of-the-art tools and their use in the decision-making process is discussed by a number of scientists from leading pharmaceutical companies.

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