Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
P53 Suppressor Gene

P53 Suppressor Gene

Mukhopadhyay, Tapas
Maxwell, Steven A.
Roth, Jack A.

Paperback

Series: Molecular Biology Intelligence Unit

Medical ReferenceBiology

ISBN10: 3662222779
ISBN13: 9783662222775
Publisher: Springer
Published: Apr 18 2014
Pages: 132
Weight: 0.79
Height: 0.33 Width: 8.25 Depth: 11.00
Language: English
This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation and other transcription factors. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy.

Also in

Medical Reference

View All