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Oxidative Stress and Redox Signalling in Parkinson's Disease

Oxidative Stress and Redox Signalling in Parkinson's Disease

Hardcover

Series: Issues in Toxicology, Book 34

Medical ReferenceBiologyChemistry

ISBN10: 1782621881
ISBN13: 9781782621881
Publisher: Royal Society of Chemistry
Published: Jul 25 2017
Pages: 520
Weight: 2.10
Height: 1.40 Width: 6.40 Depth: 9.30
Language: English

Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress can be defined as an imbalance between the production of reactive species and the ability to detoxify them and their intermediates or by-products. Oxidative damage to lipids, proteins, and DNA has been detected in autopsies from individuals with Parkinson's Disease and so links can be made between oxidative stress and Parkinson's Disease pathogenesis.

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