Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Overcoming Resistance to Egfr Inhibitors in Egfr-Mutant Nsclc: Volume 19

Overcoming Resistance to Egfr Inhibitors in Egfr-Mutant Nsclc: Volume 19

Faber, Anthony

Hardcover

Series: Cancer Sensitizing Agents for Chemotherapy, Book 19

Medical ReferenceBiology

ISBN10: 0128228334
ISBN13: 9780128228333
Publisher: Academic Press
Published: Feb 1 2023
Pages: 150
Weight: 1.10
Height: 0.51 Width: 7.61 Depth: 9.41
Language: English

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC, Volume 17 presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer.

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