Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Organ System CrossTalk in Critical Illness: From Basic Pathophysiology to Clinical Management

Organ System CrossTalk in Critical Illness: From Basic Pathophysiology to Clinical Management

Battaglini, Denise
de Rosa, Silvia
Godoy, Daniel Agustin

Hardcover

Medical Reference

ISBN10: 3032010233
ISBN13: 9783032010230
Publisher: Springer
Published: Nov 14 2025
Pages: 494
Weight: 2.24
Height: 1.06 Width: 6.52 Depth: 9.26
Language: English

This book describes deleterious inter-organ crosstalk and its mechanistic concepts, underlying the specific clinical aspect and focusing on medical clinical management in critical care.

Homeostasis and health of multicellular organisms with multiple organs depends on inter-organ communication. Tissue injury in one organ disturbs this homeostasis and can lead to disease in multiple organs, or multi-organ failure. Many routes of inter-organ crosstalk during homeostasis are relatively well known, but inter-organ crosstalk in disease still lacks understanding. Particularly, how tissue injury in one organ can drive injury at remote sites and trigger multi-organ failure with high mortality is poorly understood. Mechanistically, inter-organ crosstalk after tissue injury could involve soluble mediators and their target receptors, cellular mediators, in particular immune cells, as well as newly identified neuro-immune connections.

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