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Orexin and Sleep: Molecular, Functional and Clinical Aspects

Orexin and Sleep: Molecular, Functional and Clinical Aspects

Paperback

Medical ReferenceBiology

ISBN10: 3319352202
ISBN13: 9783319352206
Publisher: Springer Nature
Published: Aug 23 2016
Pages: 410
Weight: 1.31
Height: 0.87 Width: 6.14 Depth: 9.21
Language: English

History of Orexin Research.- The Hypocretin Story.- Input and output systems of orexin neurons.- Physiological roles of orexin receptors on sleep/wakefulness regulation.- Orexin receptor functions in the ascending arousal system (Folder name - Leonard).- Elucidation of neuronal circuitry involved in the regulation of sleep/wakefulness using optogenetics (Folder name - Yamanaka).- Modulation of thalamocortical pathways by orexins.- Orexins, Alcohol and Sleep Homeostasis.- Orexin induced modulation of REM sleep and its loss associated patho-physiological changes are mediated through locus coeruleus.- Role of orexin on sleep: interactions with other neurotransmitter systems.

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