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Optical Interferometry for Biology and Medicine

Optical Interferometry for Biology and Medicine

Hardcover

Series: Bioanalysis, Book 1

Technology & EngineeringBiology

ISBN10: 146140889X
ISBN13: 9781461408895
Publisher: Springer Nature
Published: Dec 3 2011
Pages: 354
Weight: 1.40
Height: 0.80 Width: 6.00 Depth: 9.10
Language: English

This book presents the fundamental physics of optical interferometry as applied to biophysical, biological and medical research. Interference is at the core of many types of optical detection and is a powerful probe of cellular and tissue structure in interfererence microscopy and in optical coherence tomography. It is also the root cause of speckle and other imaging artefacts that limit range and resolution. For biosensor applications, the inherent sensitivity of interferometry enables ultrasensitive detection of molecules in biological samples for medical diagnostics. In this book, emphasis is placed on the physics of light scattering, beginning with the molecular origins of refraction as light propagates through matter, and then treating the stochastic nature of random fields that ultimately dominate optical imaging in cells and tissue. The physics of partial coherence plays a central role in the text, with a focus on coherence detection techniques that allow information to be selectively detected out of incoherent and heterogeneous backgrounds.

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Biology