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Next Generation Sequencing Technologies and Challenges in Sequence Assembly

Next Generation Sequencing Technologies and Challenges in Sequence Assembly

Paperback

Series: Springerbriefs in Systems Biology, Book 7

Medical ReferenceAnatomy & PhysiologyBiology

ISBN10: 149390714X
ISBN13: 9781493907144
Publisher: Springer
Published: Apr 19 2014
Pages: 118
Weight: 0.43
Height: 0.28 Width: 6.14 Depth: 9.21
Language: English

The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field.

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Anatomy & Physiology