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Negative Co-Receptors and Ligands
Paperback
Series: Current Topics in Microbiology and Immmunology, Book 350
ISBN13: 9783642267772
Publisher: Springer
Published: May 29 2013
Pages: 152
Weight: 0.55
Height: 0.50 Width: 6.10 Depth: 9.00
Language: English
Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.
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