Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
The neuroprotective power of Tribulus

The neuroprotective power of Tribulus

Bouabdallah, Salwa

Paperback

Biology

ISBN10: 6207660684
ISBN13: 9786207660681
Publisher: Our Knowledge Publishing
Published: Jun 13 2024
Pages: 84
Weight: 0.30
Height: 0.20 Width: 6.00 Depth: 9.00
Language: English
Recently, Tribulus terrestris (Tt) has attracted increasing interest due to its pharmacological potential, including its neuroprotective activities. In this study, we explore the neuroprotective effects of a Tt extract in a zebrafish (Danio rerio) model of scopolamine (SCOP)-induced memory impairment and cerebral oxidative stress. SCOP, an anticholinergic drug, has been used to reproduce fundamental aspects of Alzheimer's disease (AD) in animal models. Fish were treated with ethanolic leaf extract (ELE) of Tt (1, 3 and 6 mg/L) for 15 days. Molecular interactions of the main compounds identified via UPLC-PDA/MS in Tt fractions with the active site of acetylcholinesterase (AChE) were explored via molecular docking analyses. Terrestrosin C, protodioscin, rutin and saponin C showed the most stable binding. Spatial memory performance was assessed using the Y-maze test, and memory recognition was assessed using the NOR test.

Also from

Bouabdallah, Salwa

View All

Also in

Biology

View All