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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Neoplastic Transformation in Human Cell Culture: Mechanisms of Carcinogenesis

Neoplastic Transformation in Human Cell Culture: Mechanisms of Carcinogenesis

Rhim, Johng S.
Dritschilo, Anatoly

Hardcover

Series: Experimental Biology and Medicine, Book 25

Medical Reference

ISBN10: 0896032272
ISBN13: 9780896032279
Publisher: Springer Nature
Published: Dec 10 1991
Pages: 396
Weight: 2.00
Height: 1.00 Width: 6.30 Depth: 9.20
Language: English
The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi- mental model systems. A workshop on neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the- art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver- sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in vitro model systems (epithelial, fibroblastic, and hematopoietic). 2. Factors modulating cellular transformation. 3. Usefulness of defined in vitro model systems for viral, chemical, and radiation carcinogenesis. 4. Multistep nature of human cell carcinogenesis. 5. Role of activated and suppressor oncogenes in neoplastic trans- formation. The workshop was organized by J. S. Rhim and A. Dritschilo (cochairmen), G. Jay, J. little, M. McCormick, R Tennant, and R R Weischelbaum. There were 32 speakers, 30 poster presentations, and about 190 participants.

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