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Nanostructures for Antimicrobial and Antibiofilm Applications

Nanostructures for Antimicrobial and Antibiofilm Applications

Hardcover

Series: Nanotechnology in the Life Sciences

Technology & EngineeringBiologyBotany & Horticulture

ISBN10: 303040336X
ISBN13: 9783030403362
Publisher: Springer Nature
Published: May 13 2020
Pages: 458
Weight: 1.84
Height: 1.06 Width: 6.14 Depth: 9.21
Language: English

In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications.

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