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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Mouse Models of Cancer: A Laboratory Manual

Mouse Models of Cancer: A Laboratory Manual

Abate-Shen, Cory
Politi, Katerina
Chodosh, Lewis

Paperback

Medical ReferenceBiology

Currently unavailable to order

ISBN10: 1621820033
ISBN13: 9781621820031
Publisher: Cold Spring Harbor Laboratory Press
Published: Nov 30 2013
Pages: 521
Weight: 3.40
Height: 1.00 Width: 8.50 Depth: 10.80
Language: English
The laboratory mouse is an important model for studying cancer and its treatment. This book includes both background information and step-by-step protocols for generating mouse models that accurately recapitulate many features of human cancer. It covers genetic models, including transgenic germline models, gene knockouts and knockins, and conditional and inducible systems, as well as models derived using chemical carcinogens, RNA interference, tissue recombination, and other strategies. Techniques to characterize tumor development, progression, and metastasis in these mice using state-of-the-art imaging, histopathological, surgical, and other approaches are described. The uses of these models in preclinical and translational research are also discussed--

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