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Monoamine Oxidase: Methods and Protocols

Monoamine Oxidase: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 2558

Medical ReferenceChemistry

ISBN10: 1071626450
ISBN13: 9781071626450
Publisher: Humana Pr
Published: Oct 2 2023
Pages: 254
Weight: 1.03
Height: 0.56 Width: 7.00 Depth: 10.00
Language: English
This detailed book examines the main methods to study mammalian monoamine oxidases (MAOs), ranging from cell biology to computational chemistry. Beginning with techniques on how to obtain pure samples of MAO A and MAO B, the volume continues by covering assays and techniques used to measure MAO enzymatic activity and perform inhibition studies, methods to address cellular localization and function of MAOs, either in cell lines or in animal models, as well as computational methods applied to rational drug design approaches that are used to develop new MAO inhibitors. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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