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Metabolism in Cancer

Metabolism in Cancer

Paperback

Series: Recent Results in Cancer Research, Book 207

Medical ReferenceChemistry

ISBN10: 3319825011
ISBN13: 9783319825014
Publisher: Springer Nature
Published: Jun 14 2018
Pages: 266
Weight: 0.87
Height: 0.58 Width: 6.14 Depth: 9.21
Language: English
This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications.Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

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