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Mouse Models for Drug Discovery: Methods and Protocols

Mouse Models for Drug Discovery: Methods and Protocols

Hardcover

Series: Methods in Molecular Biology, Book 1438

Medical Reference

ISBN10: 149393659X
ISBN13: 9781493936595
Publisher: Springer Nature
Published: May 6 2016
Pages: 436
Weight: 2.19
Height: 1.00 Width: 7.00 Depth: 10.00
Language: English
With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse. Herein, these models are applied to a wide field of disease areas, including diabetes, cardiovascular disease, skin disorders, cancer, neurodegenerative and neuromuscular diseases, retinal disorders, as well as various behavioral models. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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