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Molecular and Integrative Physiology of the Musculoskeletal System, Volume 1211
Paperback
Series: Annals of the New York Academy of Science, Book 67
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ISBN13: 9781573318310
Publisher: Wiley
Published: Dec 13 2010
Pages: 252
Weight: 0.60
Height: 0.20 Width: 6.90 Depth: 9.80
Language: English
This volume examines the musculoskeletal system a complex network of molecular signaling both within the bone and also among bone, muscle, and other organs, such as the intestine, brain, pancreas, adipose tissue, and pituitary gland. Owing to these complex pathways, there are many novel molecular targets for drug development to treat disorders that have been heretofore overlooked or neglected. These include cachexia, sarcopenia, osteoporosis, and various deconditioned states associated with an array of chronic illnesses.
New paradigms of therapeutic interventions can be realized from a systems approach and from the use of crossover therapies. The skeletal system is intensively involved with immunological and hormonal activity, and tapping these resources may provide more effective ways to manage disease.
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