Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Microneedles for CNS and Brain Drug Delivery

Microneedles for CNS and Brain Drug Delivery

Raman, Devi

Paperback

Medical Reference

ISBN10: 6630284364
ISBN13: 9786630284362
Publisher: LAP Lambert Academic Publishing
Published: Jul 22 2026
Pages: 76
Weight: 0.25
Height: 0.18 Width: 6.00 Depth: 9.00
Language: English
The delivery of therapeutics to the Central Nervous System (CNS) and brain remains one of the biggest challenges in pharmaceutics due to the presence of the Blood-Brain Barrier (BBB). Conventional routes often fail to achieve therapeutic concentrations in brain tissue while causing systemic side effects. Microneedle technology has emerged as a minimally invasive, patient-friendly platform that enables direct and targeted drug delivery across biological barriers. By bypassing the BBB through transdermal, intranasal, or direct CNS routes, microneedles can enhance drug bioavailability and localization. Recent advances have expanded the scope of microneedles from delivering small molecules to complex biologics. Integration with next-generation carriers such as exosomes for targeted delivery, and gene therapy vectors like CRISPR-Cas and mRNA, is revolutionizing CNS treatment. This convergence allows for precision therapy in neurodegenerative diseases, brain tumors, and psychiatric disorders.This chapter discusses the design principles, material advancements, and applications of microneedles for CNS and brain drug delivery.

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