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Methodology for Genetic Studies of Twins and Families

Methodology for Genetic Studies of Twins and Families

Paperback

Series: NATO Science Series D:, Book 67

Medical ReferenceGeneral SociologyGenetics

ISBN10: 9048141796
ISBN13: 9789048141791
Publisher: Springer Nature
Published: Dec 5 2010
Pages: 496
Weight: 1.60
Height: 1.05 Width: 6.14 Depth: 9.21
Language: English
Few would dispute the truth of the statement People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package.
The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

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