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Method Development and Validation of Zopiclone by RP-HPLC.

Method Development and Validation of Zopiclone by RP-HPLC.

Paperback

Medical Reference

ISBN10: 6202563710
ISBN13: 9786202563710
Publisher: Lap Lambert Academic Pub
Published: May 27 2020
Pages: 120
Weight: 0.41
Height: 0.28 Width: 6.00 Depth: 9.00
Language: English
A simple, sensitive, rapid and selective isocratic reversed phase High Performance Liquid Chromatographic (HPLC) method has been developed for Zopiclone from bulk drug using a mobile phase consisting mixture of Acetonitrile: Buffer (pH 2.8) (80:20v/v) Composition of buffer: (0.272gm in 200ml HPLC water and pH adjusted to 2.8 using ortho Phosphoric acid) at the flow rate of 1.0 mL/min. A Cosmosil C18 (250 cm x 4.6 mm, 5 μm) column was used as stationary phase.

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Medical Reference