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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Metallo Beta Lactamases Producing Pseudomonas aeruginosa isolates

Metallo Beta Lactamases Producing Pseudomonas aeruginosa isolates

Nahaei, Mohammad Reza
Farajnia, Safar
Yousefi, Saber

Paperback

Biology

ISBN10: 3659156582
ISBN13: 9783659156588
Publisher: Lap Lambert Academic Pub
Published: Jul 26 2012
Pages: 128
Weight: 0.44
Height: 0.30 Width: 6.00 Depth: 9.00
Language: English
Carbapenem resistance due to metallo beta lactamases (MBLs) has grown as a health care problem in recent decades. The present study has investigated the antibiotic susceptibility patterns and screening of MBLs producing P. aeruginosa isolates at two university hospitals in northwest of Iran. Furthermore, serotyping, PFGE and MLST were used for studying the clonal relationship among the isolates. In brief our findings showed that blaVIM and blaIMP types MBLs are common in our area. All MBLs producing isolates were non-susceptible to imipenem, majority of them belonged to MDR phenotype and O10 or O11 serotypes. Also, a multi-drug resistant clone of P. aeruginosa was identified in a burn unit in Orumieh- Iran, which majority of them belonged to O10 serotype, and most of them were sequence type, ST773. In conclusion, since MBLs producing isolates are resistant to most antibacterial agents, early detection of such isolates is crucial to choose appropriate therapeutic regimens and prevent dissemination of this type of resistance. Finally our findings emphasize the importance of continually following the epidemiological relatedness of MDR P. aeruginosa spreading in ICUs and burn units.

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