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Magnetic resonance imaging for initial diagnosis of sporadic Creutzfeldt Jakob disease: Case series and review

Magnetic resonance imaging for initial diagnosis of sporadic Creutzfeldt Jakob disease: Case series and review

Paperback

Medical Reference

ISBN10: 366898929X
ISBN13: 9783668989290
Publisher: Grin Verlag
Published: Aug 6 2019
Pages: 40
Weight: 0.14
Height: 0.10 Width: 5.83 Depth: 8.27
Language: English
Scientific Study from the year 2019 in the subject Medicine - Radiology, Nuclear Medicine, Medizinische Universität Graz (Radiologie), language: English, abstract: The aim of this case series is to show the reliability of magnetic resonance imaging (MRI) in the initial diagnosis of this disease and demonstrate its advantages compared to other modalities. We also compared our cases with other larger studies and give a review of literature to confirm our observations. Sporadic Creutzfeldt-Jakob disease (sCJD) is a uniformly fatal neurodegenerative disorder caused by the accumulation of an abnormal form of the human prion protein in the brain. It typically presents as a rapidly progressive dementia (RPD). For a definitive diagnosis, brain biopsy or autopsy is required (definite CJD). Premortal diagnosed patients are called probable CJD according to the diagnostic criteria of Zerr et al. So this entity can be difficult to identify antemortem.

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Medical Reference