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Macromolecular Crystallography Protocols, Volume 1: Preparation and Crystallization of Macromolecules
Paperback
Series: Methods in Molecular Biology, Book 363
ISBN13: 9781617374753
Publisher: Springer Nature
Published: Nov 10 2010
Pages: 280
Weight: 0.96
Height: 0.67 Width: 6.00 Depth: 9.00
Language: English
Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1, Preparation and Crystallization of Macromolecules and Volume 2, Structure Determination, explore recent advances that have accelerated the pace of structural determination and made crystallography accessible to a broader range of investigators.
Volume 1 is composed of detailed protocols for the preparation and optimization of crystals, including tips from the experts on the best methods for inducing proteins to adopt their crystalline form. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization, as well as computational techniques for data collection, phasing, and refinement. The volume concludes with a detailed and insightful survey of available crystallographic software. These volumes will be an indispensable reference for obtaining macromolecular crystals and determining their three-dimensional structure.
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