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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Lipid Hydroperoxide-Derived Modification of Biomolecules

Lipid Hydroperoxide-Derived Modification of Biomolecules

Kato, Yoji

Paperback

Series: Subcellular Biochemistry, Book 77

Medical ReferenceTechnology & EngineeringChemistry

ISBN10: 9402402969
ISBN13: 9789402402964
Publisher: Springer Nature
Published: Sep 17 2016
Pages: 202
Weight: 0.67
Height: 0.45 Width: 6.14 Depth: 9.21
Language: English
Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is formed in an initial step of lipid peroxidation. Lipid hydroperoxide is also known as a potential source of singlet oxygen. Harmful aldehydes are formed when the lipid hydroperoxide is degraded. The formed aldehyde has high reactivity against thiol or amine moieties. Therefore, it could act as a signaling molecule, which might induce the changing of gears inside a cell. Recent studies have shown that lipid hydroperoxide or a slightly modified product of the lipid hydroperoxide reacts with biomolecules such as proteins and aminophospholipids, which leads to formation of amide-type adducts. Amide-type adducts could be one of markers for oxidative stress and could also be an important player in some diseases. In this book, the chemistry and biochemistry of lipid hydroperoxide along with their conjugates with biomolecules are described.

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