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Levodopa-Induced Dyskinesia in Parkinson's Disease

Levodopa-Induced Dyskinesia in Parkinson's Disease

Hardcover

Medical ReferenceCognition

ISBN10: 1447165020
ISBN13: 9781447165026
Publisher: Springer
Published: Oct 23 2014
Pages: 368
Weight: 1.56
Height: 0.88 Width: 6.14 Depth: 9.21
Language: English

This book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from 'bench to bedside'.

Initial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID. The following chapters cover the latest preclinical studies aiming to understand the pathophysiology of LID at the cellular, neurochemical, neurophysiological and circuitry level with detailed discussion of mechanisms and future directions to take the field forward; clinical studies from phase II to phase IV; on going RCTs in LID and evidence-based medicine reviews of treatment options.

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