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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Lateral Hypothalamic Control of Energy Balance

Lateral Hypothalamic Control of Energy Balance

Kurt, Gizem
Woodworth, Hillary L.
Leinninger, Gina M.

Paperback

Series: Colloquium Integrated Systems Physiology: From Molecule to Function to Disease

Anatomy & PhysiologyCognition

ISBN10: 1615047654
ISBN13: 9781615047659
Publisher: Morgan & Claypool
Published: Dec 6 2017
Pages: 106
Weight: 0.48
Height: 0.25 Width: 7.50 Depth: 9.25
Language: English
Food and water are necessary for survival, but can only be obtained via ingestive behavior (feeding, drinking, and moving). Survival thus depends on the ability of the brain to coordinate the need for water and energy with appropriate behaviors to modify their intake as necessary for homeostasis. However, the balance of these behaviors also inherently determines body weight, and imbalances contribute to the development of weight disorders, such as obesity and anorexia nervosa. The lateral hypothalamic area (LHA) of the brain is anatomically positioned to coordinate the sensation of osmotic and energy status with goal-directed ingestive behaviors necessary to maintain homeostasis and body weight, and, hence, may hold insight into the potential treatment for energy balance disorders. This volume reviews the essential role of the LHA for the control of body weight, from its historical description as a feeding center to the current view of this LHA as a cellularly heterogeneous hub that regulates multiple aspects of physiology to influence body weight. Furthermore, we evaluate how specific LHA populations coordinate certain metabolic cues and behaviors, which may guide the development of pathway-specific interventions to improve the treatment of energy balance disorders.

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