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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Kisspeptin Signaling in Reproductive Biology

Kisspeptin Signaling in Reproductive Biology

Kauffman, Alexander S.
Smith, Jeremy T.

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 784

Medical ReferenceGenetic Conditions

ISBN10: 1461461987
ISBN13: 9781461461982
Publisher: Springer Nature
Published: Apr 2 2013
Pages: 514
Weight: 1.95
Height: 1.40 Width: 6.30 Depth: 9.10
Language: English
Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.

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