Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Interferon Alpha and Ribavirin Induced Thyroid Dysfunction

Interferon Alpha and Ribavirin Induced Thyroid Dysfunction

Nadeem, Amina
Aslam, Muhammad

Paperback

Medical Reference

ISBN10: 384737513X
ISBN13: 9783847375135
Publisher: Lap Lambert Academic Pub
Published: Mar 6 2012
Pages: 160
Weight: 0.54
Height: 0.37 Width: 6.00 Depth: 9.00
Language: English
According to WHO studies, approximately 170 million individuals of the world population are diagnosed to be infected with Hepatitis C virus. Unfortunately around 20 % of these patients experience progressive liver disease leading to cirrhosis or hepatocellular carcinoma over 20 to 40 years. Interferon-alpha and ribavirin combination therapy is the standard treatment for chronic hepatitis C. These drugs may trigger production of different types of non-specific and specific autoantibodies. Thyroid dysfunction, which has been reported to occur from 3.9-33.33%, is the most common autoimmune disorder associated with combination therapy. Therefore, it is necessary that thyroid functions are monitored during therapy and the course of thyroid disease is watched for once autoimmune thyroid disorder develops. This book highlights the effects of Interferon and ribavirin on thyroid functions, its pathogenesis, clinical features and outcome through a cohort study carried out on chronic hepatitis C patients.

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