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In Situ Hybridisation

In Situ Hybridisation

Hardcover

Series: Society for Experimental Biology Seminar, Book 40

Biology

ISBN10: 0521380626
ISBN13: 9780521380621
Publisher: Cambridge
Published: Aug 31 1990
Pages: 302
Weight: 1.26
Height: 0.69 Width: 6.00 Depth: 9.00
Language: English
Advances in our understanding of biological mechanisms have frequently been associated with the development of new techniques. In situ hybridization is a classic case of just such an advance. The technique effectively combines histochemistry with molecular biology and enables the rapid analysis of the distribution of RNA, or DNA, in the tissues. The information gained from this has caused something of a revolution in our understanding of developmental biology, since a fundamental aspect of development is the spatial and temporal expression of genes. In addition the technique has found application in the field of medicine, where it is giving new insights into the functioning of healthy tissues and the diagnosis and study of diseases. This book brings together contributions from leaders in the application of this technique and will help the reader review and be guided through the various options and variations of the technique.

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Biology