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Immune Complexes and Human Cancer

Immune Complexes and Human Cancer

Paperback

Series: Contemporary Topics in Immunobiology, Book 15

Medical Reference

ISBN10: 1468449338
ISBN13: 9781468449334
Publisher: Springer Nature
Published: Apr 29 2012
Pages: 280
Weight: 0.89
Height: 0.63 Width: 6.00 Depth: 9.00
Language: English
Immune Complexes and Human Cancer, the fifteenth volume of Contem- porary Topics in Immunobiology, is a compilation of information derived from recent studies on the role of circulating immune complexes (CIC) in the patho- genic manifestations of a variety of human cancers. Technical improvements in the detection of CIC in body fluids have resulted in data that indicate that CIC do occur in different types of cancer. In addition, tumor-associated antigens and antibodies have been detected in immune complexes of cancer patients' sera. Until recently the exact role and clinical relevance of immune complexes have been the subject of debate, partially because of the problems encountered in measuring immune complexes. But these problems are being confronted as more accurate measurement protocols are developed. Technical refinements, along with strict protocols, have provided evidence of heterogeneity in CIC, a factor that makes accurate detection of immune complexes in cancer patients difficult. Recent insights indicate that the measurement of immune complexes in cancer patients may be clinically useful not only as a tumor marker, but also in regard to the deranged immune response of tumor-bearing hosts and other disorders such as nephrotic syndrome, immune anemias, and clotting dysfunction.

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