Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
La leucemia mielomonocitica cronica (CMML)

La leucemia mielomonocitica cronica (CMML)

Zahradnik, Michaela

Paperback

Medical Reference

ISBN10: 6209013759
ISBN13: 9786209013751
Publisher: Edizioni Sapienza
Published: Aug 23 2025
Pages: 120
Weight: 0.38
Height: 0.28 Width: 6.00 Depth: 9.00
Language: Italian
Chronic myelomonocytic leukemia is a hematological neoplasm that develops as a result of clonal degeneration of hematopoietic stem cells. The first sign of the disease is an increase in the number of monocytes in the peripheral blood. In addition to cell proliferation, dysplastic hematopoiesis is also usually present. The diagnosis of CMML is difficult due to the heterogeneity of the clinical, hematological, and morphological presentation and the lack of specific cytogenetic changes. In addition to distinguishing it from other hematological neoplasms, reactive monocytosis must be ruled out before a diagnosis can be made. Due to their immunological function, monocytes are increased in a variety of inflammatory and chronic processes as well as in tumor diseases. This research project investigated whether flow cytometric analysis of CD56 expression on monocytes in the presence of absolute monocytosis in peripheral blood is suitable for distinguishing reactive cell proliferation from clonal processes. The study was conducted in collaboration with Andrea Hauser, MSc, and Dr. Karl Schrattbauer.

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