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Invertebrate Cytokines and the Phylogeny of Immunity: Facts and Paradoxes
Paperback
Series: Progress in Molecular and Subcellular Biology, Book 34
Medical ReferenceBiologyChemistry
ISBN13: 9783642622366
Publisher: Springer Nature
Published: Nov 22 2012
Pages: 184
Weight: 0.63
Height: 0.42 Width: 6.14 Depth: 9.21
Language: English
Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates. Until recently, most of our knowledge of cytokine- and cytokine receptor-like molecules in invertebrates has relied on functional assays and similarities at the physicochemical level. As such, a phylogenetic relationship between invertebrate cytokine-like molecules and invertebrate counterparts could not be convincingly demonstrated.
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