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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Intricacies of T Cell Activation and Signaling

Intricacies of T Cell Activation and Signaling

Fabian, Ebenezer Chitra

Paperback

Medical ReferenceBiology

ISBN10: 3639074548
ISBN13: 9783639074543
Publisher: Blues Kids Of Amer
Published: Oct 6 2008
Pages: 104
Weight: 0.33
Height: 0.22 Width: 6.00 Depth: 9.00
Language: English
T cell signal transduction is not a linear pathway, but involves multiple components acting as a network. Though CD8 T cells are capable of being stimulated with a brief stimulus, recent studies have brought to focus the persistence of signaling in T cells post synaptic engagement. Though these signals are not strong enough for direct detection, their effect on functional maturity of T cells is ascertained by functional assays. Different outcomes of activated T cells do exhibit a certain level of hierarchy in the order of activation and the strength of signal required for each. The intracellular signaling components seem to form modules involved in persistence of signaling in T cells. This book provides an overview of T cell activation focusing on CD8 T cells.

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