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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Intracellular Signal Transduction: The Jak-Stat Pathway

Intracellular Signal Transduction: The Jak-Stat Pathway

Wilks, Andrew F.
Harpur, Ailsa G.

Paperback

Series: Molecular Biology Intelligence Unit

Medical ReferenceBiologyChemistry

ISBN10: 3662220520
ISBN13: 9783662220528
Publisher: Springer Nature
Published: Nov 13 2013
Pages: 209
Weight: 0.86
Height: 0.46 Width: 7.00 Depth: 10.00
Language: English
This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.

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