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The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease

The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease

Hardcover

Medical Reference

Currently unavailable to order

ISBN10: 3709115345
ISBN13: 9783709115343
Publisher: Springer Pg
Published: Sep 13 2013
Pages: 446
Weight: 3.60
Height: 1.20 Width: 8.40 Depth: 11.00
Language: English

The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain.

Written by leading scientists and clinicians, the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques.

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