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Interaction of Nanomaterials with the Immune System

Interaction of Nanomaterials with the Immune System

Paperback

Series: Molecular and Integrative Toxicology

Medical ReferenceTechnology & Engineering

ISBN10: 3030339645
ISBN13: 9783030339647
Publisher: Springer Nature
Published: Jan 31 2021
Pages: 223
Weight: 0.74
Height: 0.50 Width: 6.14 Depth: 9.21
Language: English
Overview of immune response to nanomaterials caused by either inhalation, oral, or dermal exposure.- Engineered nanomaterials: synthesis, characterization, uses and exposure.- Impact of nanomaterials on barrier function.- Complement activation and inflammation.- Macrophage function and phagocytosis.- Mast cells.- Impact on dendritic cell - lymphocyte function.- Impact on host pathogen response and microbiome.- Allergy/autoimmunity.- Pre-existing allergic or bacterial-induced lung disease.- Nanomaterial effects on viral infection.- Immunotoxicity and carcinogenesis.- In vivo animal models (nude mice, transgenic models).- In vitro cell culture models.- In silico computational modeling.- Summary of mechanisms of immune modulation.

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