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Insights Into Receptor Function and New Drug Development Targets

Insights Into Receptor Function and New Drug Development Targets

Paperback

Series: Research and Perspectives in Endocrine Interactions

Medical ReferenceBiology

Currently unavailable to order

ISBN10: 3642070809
ISBN13: 9783642070808
Publisher: Springer Pg
Published: Nov 22 2010
Pages: 202
Weight: 0.69
Height: 0.46 Width: 9.21 Depth: 6.14
Language: English

We are now on the verge of viewing effector molecules and other regulatory sites as therapeutic targets for the amelioration of human and animal disease. The recognition, for example, that mutant proteins are frequently misrouted molecules, rather than functionally defective ones, changes our approach to inborn errors of metabolism and offers new approaches for pharmacological discovery, based on rescue of receptors, ion channels and enzymes with pharmacoperones. Ion channels, regulators of G-protein signaling and enzymes engaged in regulation, now present opportunities for drug development.

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