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Industrialization of Drug Discovery: From Target Selection Through Lead Optimization

Industrialization of Drug Discovery: From Target Selection Through Lead Optimization

Hardcover

Series: Drug Discovery, Book 2

Medical ReferenceChemistry

ISBN10: 0824723910
ISBN13: 9780824723910
Publisher: CRC Press
Published: May 1 2005
Pages: 328
Weight: 1.31
Height: 0.91 Width: 6.36 Depth: 9.56
Language: English
The pharmaceutical industry suffers from an innovation deficit, with clinical attrition and safety-related market-withdrawal rates at the same level as twenty years ago. This book scrutinizes this problem in detail, contrasting the promise of technology and industrialization with the apparent inability of industry to fully realize the tools that are available. The text begins by introducing the evolution of modern drug discovery, tracing it from basic concepts to current approaches. The editor devotes the remainder of the discussion to the regulatory environment, industrialization, compound and knowledge management functions, the drug screening process, collaboration, and finally, ethical issues.

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Handen Ph. D., Jeffrey S.

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Medical Reference