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Histone Recognition
Hardcover
Medical ReferenceChemistryGenetics
ISBN13: 9783319181011
Publisher: Springer
Published: Jun 10 2015
Pages: 282
Weight: 1.29
Height: 0.69 Width: 6.14 Depth: 9.21
Language: English
The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription.- PHD Fingers as Histone Readers.- Methyl-Lysine Recognition by the Royal Family Modules: Chromo, Tudor, MBT, Chromo Barrel, and PWWP Domains.- Histone Recognition by WD40 Proteins.- Methyl-Lys Recognition by Ankyrin Repeat Proteins.- Methyl-Arginine Recognition by Tudor Domains.- Histone Recognition by Tandem Modules and Modulation by Multiple PTMs.- Genome-Wide Profiling of Molecular Recognition of Histone PTMs.- BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies.- Anti-Inflammatory Effects of BET Protein Inhibition Through Modulation of Gene Transcription.- Activating Latent HIV by Inhibiting Bromodomain Proteins.- Small Molecule Modulation of Methyl-Lysine Mediated Interactions.
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