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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Histone Deacetylases: Transcriptional Regulation and Other Cellular Functions

Histone Deacetylases: Transcriptional Regulation and Other Cellular Functions

Verdin, Eric

Paperback

Series: Cancer Drug Discovery & Development

Medical Reference

ISBN10: 1617376027
ISBN13: 9781617376023
Publisher: Springer Nature
Published: Nov 19 2010
Pages: 352
Weight: 1.04
Height: 0.74 Width: 6.00 Depth: 9.00
Language: English
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.

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