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Histological Typing of Soft Tissue Tumours

Histological Typing of Soft Tissue Tumours

Paperback

Series: Who. World Health Organization. International Histological C

Medical Reference

ISBN10: 3540567941
ISBN13: 9783540567943
Publisher: Springer Nature
Published: Feb 28 1994
Pages: 142
Weight: 0.51
Height: 0.34 Width: 6.14 Depth: 9.21
Language: English
The first edition of Histological Typing of Soft Tissue Tumours, pub- lished in 1969, represented a major step in the standardization of nomen- clature in this specialty area. Accompanied by a glass slide set of more than a hundred common and exotic tumours, this book resulted in the rapid assimilation of a universal set of guidelines and diagnostic defini- tions by pathologists in many countries. In the intervening two decades numerous changes have occurred, and our committee has been chal- lenged by the desire to incorporate new and exciting findings from the areas of immunohistochemistry and molecular biology into the classifi- cation with the need to develop a simple reproducible classification for practising pathologists. The current system, while based principally on standard microscopic observations, acknowledges and cites the use of di- agnostically valuable ancillary techniques. Changes in the Classification Although the original classification utilized the concept of histogene- sis or tissue of origin in defining tumours, we have departed from that point of view, acknowledging the impossibility of determining histogen- esis by morphologic means alone. This classification is based on the line of differentiation, or stated simply, by comparing tumours to the nor- mal cell they most closely resemble without necessarily implying origin therefrom. As in the old classification we have interpreted the term tu- mours in the broadest sense of the word and have, therefore, included neoplastic and non-neoplastic conditions.

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