Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Hif-1 as a Potential Drug Target for Solid Tumors

Hif-1 as a Potential Drug Target for Solid Tumors

Manohar, Sonal
Majithiya, Kinjal
Guralwar, Palak

Paperback

Biology

ISBN10: 6208010675
ISBN13: 9786208010676
Publisher: LAP Lambert Academic Publishing
Published: Sep 30 2024
Pages: 100
Weight: 0.35
Height: 0.24 Width: 6.00 Depth: 9.00
Language: English
Hypoxia is a typical microenvironmental characteristic of many solid tumors. HIF-1 is the key regulator of growing tumor's response to hypoxia. HIF-1α subunit levels rise in hypoxic environments, when oncogenes are activated, and/or when tumor suppressor genes are inactivated, this is necessary for HIF-1 function in tumors. HIF-1 turns on genes that enable cells of a solid tumor to flourish in the noxious hypoxic tumor environment via attainment of numerous cancer hallmarks. This book elaborates the regulation and role of HIF-1 in oncogenic signalling. Further, its potential as a drug target for solid tumors is also discussed. The book will be useful as a reference book for students of graduate and post-graduate level courses in Life Science, Biomedical Science as well as to those who have a special interest in Cancer Biology.

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Biology

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