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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia

Maatamri, Wided
Thameur, Fatma

Paperback

Biology

ISBN10: 6208986753
ISBN13: 9786208986759
Publisher: Our Knowledge Publishing
Published: Jun 20 2025
Pages: 96
Weight: 0.31
Height: 0.23 Width: 6.00 Depth: 9.00
Language: English
Heparin-induced thrombocytopenia is a complex clinico-biological condition associated with heparin therapy, a true anticoagulant standard, and paradoxically responsible for a major pro-thrombotic state. It represents the most serious iatrogenic complication of heparin therapy, and requires early diagnosis and effective treatment. Its management constitutes a genuine therapeutic emergency, requiring the use of non-heparin antithrombotic agents such as danaparoid sodium and direct thrombin inhibitors to inhibit the hypercoagulability induced by explosive thrombin generation. Biological diagnosis can sometimes be difficult, despite the progress made in understanding the mechanism of the disease and the development of immunological and functional tests that offer diagnostic performance and numerous advantages. One of the most effective functional tests is the radiolabeled serotonin release assay (RAS), historically considered the gold standard.

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