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Heat Shock Proteins of Malaria

Heat Shock Proteins of Malaria

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 1340

Medical ReferenceBiologyChemistry

ISBN10: 3030783960
ISBN13: 9783030783969
Publisher: Springer Nature
Published: Sep 27 2021
Pages: 251
Weight: 1.22
Height: 0.63 Width: 6.14 Depth: 9.21
Language: English
This new edition describes the role of heat shock proteins in the life cycle of malaria parasites, particularly in the context of intracellular parasite stages. Thoroughly revised, this work provides a general introduction to the structural and functional features of heat shock proteins with a special focus on their role as molecular chaperones in ensuring protein quality control. The emphasis is on the heat shock protein families from Plasmodium falciparum, and their role in proteostasis and the development of malaria pathology. Moreover, the authors explore the latest prospects of targeting heat shock proteins in antimalarial drug discovery either directly or in combination therapies.

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